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Applications of Graphene Composites in Bone Repair

Jiaxun Yu
Vol.5, No.4, pp.48-55, 2026 DOI: 10.62051/ijmsts.v5n4.06 August 27, 2026
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Abstract: In clinical orthopedics, the effective management of bone defects remains a major challenge. Conventional options—including autografts, allografts, and synthetic substitutes—are often limited by insufficient mechanical strength, weak osteoinductive capability, and poor antimicrobial performance. In contrast, graphene and its related derivatives possess a distinct two-dimensional architecture combined with outstanding mechanical strength, electrical conductivity, and biocompatibility, making them promising promising novel modifying agents for applications in bone tissue engineering. This review systematically summarizes the recent progress of graphene-based composites used in bone repair, with emphasis on their functional mechanisms serving as mechanical reinforcement frameworks, osteoinductive factors, electroactive interfaces, antibacterial barriers and immunomodulatory components. It summarizes application cases of graphene composites with matrix materials including hydroxyapatite, polylactic acid and chitosan, and highlights the advantages of such materials in repairing large-segment bone defects and infectious bone defects. Graphene-based composites can markedly enhance the mechanical strength of scaffolds, facilitate osteogenic differentiation and angiogenesis, and achieve synergistic antibacterial and anti-inflammatory effects, offering new strategies and material prospects for clinical bone repair.
Keywords: Graphene, Bone repair, Tissue engineering scaffold, Osteogenic differentiation, Biocomposite materials
APA Citation: Jiaxun Yu (2026). Applications of Graphene Composites in Bone Repair. International Journal of Materials Science and Technology Studies, 5(4), 48-55. https://doi.org/10.62051/ijmsts.v5n4.06

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